Cleveland Guardians Strikeouts Leaders

Career totals with the Guardians and the best single seasons in club history. Records run through the 2025 season.

Jim Thome holds the Guardians career record with 1,400 strikeouts. The single-season record is 194, by Mike Napoli in 2016.

All-time Guardians leaders

Career totals with the club

#	Player	With the club	SO	G
1	Jim Thome	1991–2011	1,400	1,399
2	Carlos Santana	2010–2025	1,049	1,450
3	Jason Kipnis	2011–2019	910	1,121
4	Travis Hafner	2003–2012	882	1,078
5	Jose Ramirez	2013–2026	871	1,734
6	Jhonny Peralta	2003–2010	826	923
7	Grady Sizemore	2004–2011	816	892
8	Larry Doby	1947–1958	805	1,235
9	Manny Ramirez	1993–2000	780	967
10	Brook Jacoby	1984–1992	738	1,240
11	Andre Thornton	1977–1987	683	1,225
12	Asdrubal Cabrera	2007–2014	666	914
13	Jim Hegan	1941–1957	664	1,526
14	Kenny Lofton	1992–2007	652	1,276
15	Casey Blake	2003–2008	648	810
16	Max Alvis	1962–1969	642	951
16	Cory Snyder	1986–1990	642	657
18	Woodie Held	1958–1964	629	855
19	Shin-Soo Choo	2006–2012	626	685
20	Albert Belle	1989–1996	622	913
21	Omar Vizquel	1994–2004	586	1,478
22	Yan Gomes	2013–2018	578	609
23	Julio Franco	1983–1997	543	1,088
24	Joe Carter	1984–1989	516	839
25	Bob Feller	1936–1956	505	570

Best seasons in club history

#	Player	Season	SO	G
1	Mike Napoli	2016	194	150
2	Jim Thome	2001	185	156
3	Jim Thome	1999	171	146
3	Jim Thome	2000	171	158
5	Cory Snyder	1987	166	157
6	Gabriel Arias	2025	162	129
7	Grady Sizemore	2007	155	162
8	Grady Sizemore	2006	153	162
9	Jhonny Peralta	2006	152	149
10	Shin-Soo Choo	2009	151	156
11	Shin-Soo Choo	2012	150	155
12	Franmil Reyes	2021	149	115
13	Jason Kipnis	2016	146	156
13	Jhonny Peralta	2007	146	152
13	Jim Thome	1997	146	147
16	Jason Kipnis	2013	143	149
17	Drew Stubbs	2013	141	146
17	Jim Thome	1998	141	123
17	Jim Thome	1996	141	151
20	Casey Blake	2004	139	152
20	Jim Thome	2002	139	147
22	Nick Swisher	2013	138	145
23	Brook Jacoby	1986	137	158
24	Bobby Bonds	1979	135	146
24	Kyle Manzardo	2025	135	142